Malbrán is a faculty member at New York University in Buenos Aires and Universidad de San Andrés in Argentina. She was Visiting Professor in the Graduate Program “Kulturen der Kritik” at Leuphana Universität in Germany (2019, 2018), and Craig M. Cogut Visiting Professor in Latin American and Caribbean Studies at Brown University (2017).

As a curator, Malbrán has organized exhibitions in Argentina, the United States, Canada, Brazil, Colombia, and Paraguay. She has held curatorial positions at the MALBA - Museo de Arte Latinoamericano and the Museum of Modern Art in Buenos Aires, and the Pinacoteca do Estado in São Paulo. She has been in residence in France, Switzerland, and Spain, and was the Hilla Rebay International Fellow at the Guggenheim Museums in New York, Bilbao, and Venice. With a focus on modern and contemporary Latin American art, she has also worked closely with individual collectors and institutions in the selection and acquisition of works of art, expansion and consolidation of collections through programming and meaningful collaborations with institutions, and implementation of projects and logistics.

Her book titled La prueba del presente: ensayos sobre arte contemporáneo (Beatriz Viterbo Editora, 2023) examines artists and writers who push at the limits of form and genre, and even subvert the boundaries between the verbal and the visual. This book has been deemed influential in r eshaping debates about contemporary Latin American culture, highlighting local works in a global context.

Selected catalog writing includes essays on Clorindo Testa, Frida Kahlo, Diego Rivera, and Emilio Pettoruti for “Stranieri Ovunque - Foreigners Everywhere,” the catalog of the 60th Biennale di Venezia, 2024; on Guillermo Kuitca and Pablo Siquier for Argentina’s La Nación book series on seminal national artists; on Ernesto Neto for the Astrup Fearnley Museum of Modern Art; and on Ragnar Kjartansson for the Icelandic Pavilion at the 53rd Venice Biennale.